WALS — Modulating Immunity Through Ligand-Receptor Engineering

LECTURE SUMMARY: " I will discuss insights into immunoreceptor signaling and therapeutic modulation based on structure-based protein engineering. I will mainly focus on cytokine systems but will also delve into other axes. The overall principles focus on the exploitation of induced proximity at the cell surface to therapeutically manipulate signaling. LECTURE OBJECTIVES: (1) Tuning cytokine signaling through perturbation of the cell surface receptor complex; (2) Strategies to reduce cytokine pleiotropy for therapeutics; (3) Extension of concepts of induced proximity to discovery new signaling axes.For more information go tohttps://oir.nih.gov/walsAir date: 5/10/2023 2:00:00 PM

Source: Videocast - All Events - April 3, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video