Chronic kidney disease induced by adenine. A suitable model of growth retardation in uremia.

In conclusion, adenine-induced CKD in young rats is associated with growth retardation and disturbed endochondral ossification. This animal protocol may be a useful new experimental model to study growth in CKD.
PMID: 25972508 [PubMed - as supplied by publisher]

Source: Am J Physiol Renal P... - May 13, 2015 Category: Urology & Nephrology Authors: Claramunt D, Gil-Peña H, Fuente R, García-López E, Loredo V, Hernández Frías O, Ordóñez FA, Rodríguez-Suárez J, Santos F Tags: Am J Physiol Renal Physiol Source Type: research