The association of intrapartum deceleration and acceleration areas with MRI findings in neonatal encephalopathy

CONCLUSION: In neonates treated for HIE, acceleration area and acceleration-to-deceleration ratio are associated with the risk of neonatal brain MRI abnormalities. To increase the role of these measurements as a relevant clinical tool, larger, more powered prospective trials are needed, using computerized real-time analysis.IMPACT: The current cardiotocography predictive value for neonatal outcome is limited. This study aimed to assess the association of intrapartum deceleration and acceleration areas with the degree of cerebral injury in early cerebral MRI of neonates with encephalopathy. Lower acceleration area and acceleration-to-deceleration ratio were found to be associated with a higher degree of neonatal brain injury. Brain MRI is a marker of long-term outcome; its association with cardiotocography indices supports their association with long-term outcome in these neonates. Future computer-based CTG area analysis could assist in delivery room decision making to better time interventions and prevent hypoxic-ischemic encephalopathy.PMID:36964444 | DOI:10.1038/s41390-023-02575-5

Source: Pediatric Research - March 25, 2023 Category: Pediatrics Authors: Neta Geva Yael Geva Shimrit Yaniv Salem Kyla Anna Marks Reut Rotem Ramy Abramsky Reli Hershkovitz Ilan Shelef Evelyn Farkash Novik Adi Yehuda Weintraub Eilon Shany Source Type: research