Identification of a CEACAM5 targeted nanobody for positron emission tomography imaging and near-infrared fluorescence imaging of colorectal cancer

CONCLUSION: Collectively, we presented the identification and in vivo validation of a CEACAM5-targeted nanobody and a fused nanobody with an ABD, which enabled to the non-invasive visualization of malignancy of CRC using PET imaging and NIR imaging in subcutaneous models as well as LNM models.PMID:36914753 | DOI:10.1007/s00259-023-06183-7

Source: Molecular Medicine - March 14, 2023 Category: Molecular Biology Authors: Yitai Xiao Chaoming Mei Duo Xu Fan Yang Meilin Yang Lei Bi Junjie Mao Pengfei Pang Dan Li Source Type: research