The effect of cilostazol on the platelet-derived growth factor-beta/beta isoform reduction on venous hyperplasia in an experimental balloon-induced injury model

CONCLUSIONS: Cilostazol induced a significant reduction of IH caused by barotrauma in the venous endothelium, which correlates with decrease in the PDGF-BB in serum. This could be attributed to the pharmacologic effect on PDGFR expression.PMID:36911886 | DOI:10.1177/17085381231162160

Source: Vascular - March 13, 2023 Category: Surgery Authors: Hugo Laparra-Escare ño Alette Ortega-G ómez Alejandro Zentella-Dehesa Joaquin Manzo-Merino Carlos Acxel Vergara-Ascencio Maria Del Carmen Antu ñano-Blanco Jose Roberto Lopez-Santacruz Eduardo Esteban Montalvo-Jave Javier E Anaya-Ayala Rodrigo Lozano-Co Source Type: research