Studying ferroptosis and iron metabolism pre- and post-radiotherapy treatment in breast cancer patients

CONCLUSION: Radiotherapy induced ferroptosis in breast cancer patients as a new cell death mechanism and PTGS2 is a biomarker of ferroptosis. Iron modulation is a useful approach for the treatment of BC especially if combined with targeted therapy and immune-based therapy. Further studies are warranted to be translated into clinical compounds.PMID:36847926 | DOI:10.1186/s43046-023-00162-7
Source: J Egypt Natl Canc In... - Category: Cancer & Oncology Authors: Source Type: research