Neurochemical and microstructural alterations in bipolar and depressive disorders: A multimodal magnetic resonance imaging study

ConclusionThe findings demonstrated that both patients with UD and BD have abnormal microstructure and metabolic alterations, and the changes are not completely consistent in the prefrontal lobe region. Elevated Glu, Cho, and GluCEST% in the ACC and VPFWM of patients with UD and BD may help in differentiating between these two disorders. Our findings support the significance for the microstructural integrity and brain metabolic changes of the prefrontal lobe region in BD and UD.
Source: Frontiers in Neurology - Category: Neurology Source Type: research