Clinical outcomes and toxicities of 100 patients treated with proton therapy for chordoma on the Proton Collaborative Group Prospective Registry

CONCLUSIONS: In our series, PBT achieved excellent safety and efficacy outcomes with very low rates of treatment failure. CNS necrosis is exceedingly low (<1%) despite the high doses of PBT delivered. Further maturation of data and larger patient numbers are necessary to optimize therapy in chordoma.PMID:36813169 | DOI:10.1016/j.radonc.2023.109551

Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - February 22, 2023 Category: Radiology Authors: Stephanie R Rice Arpit M Chhabra Adam Holtzman J Isabelle Choi Shaakir Hasan Robert H Press John Chang Lia Halasz Henry K Tsai Chiachien Jake Wang Peyman Kabolizadeh Vinai Gondi William F Hartsell Sujay A Vora Carlos E Vargas Charles B Simone Source Type: research