A Workplace Tuberculosis Case Investigation in the Presence of Immigrant Contacts from High Prevalence Countries
Abstract The highest prevalence of tuberculosis (TB) occurs in foreign born immigrants in the United States. Contact investigations at work sites with mostly immigrant workers present multiple practical problems. Recently 402 contacts were investigated at a meat packing plant in rural Texas by the Texas Department of State Health Services (DSHS). Our objective was to study the approach and effectiveness of this intensive investigation. We reviewed information, including symptoms, BCG status, TB history, X-rays, and treatment, on the sentinel case and 47 contacts managed by the Texas DSHS TB Division in Lubbock, TX. We used a gamma interferon release assay (T-SPOT.TB) to identify contacts with TB infection. The sentinel case was foreign born and had cavitary TB with acid-fast positive smears. Forty-two work site contacts were foreign born, and five were US born. The foreign born contacts were from Sudan, Somalia, Mexico, Burma, and Haiti; 18 contacts had a history of BCG vaccination. T-SPOT.TB tests were positive in 20 contacts, borderline in four, and negative in 23. Contacts with borderline results had negative repeat tests. Twenty-three contacts with negative T-SPOT.TB tests were scheduled for repeat tests in 4 weeks, but only four returned for this testing. Chest X-rays were abnormal in two contacts who were started on treatment. Sputum was collected in three individuals; one was culture positive for pan-sensitive Mycobacterium tuberculosis. Twelve conta...
ConclusionIn residential settings, sufficient exposure to a variety of dusts, primarily silica-based dusts as well as those containing other less-fibrogenic materials, such as carbon, silicates and iron, have been shown to cause mixed-dust pneumoconiosis. In settings where the incidence of TB is very high, such as South Africa, the diagnosis of MDP might be overlooked due to the similarities of both diseases in their radiological presentations, especially when a detailed history of domestic exposure is omitted.
[Premium Times] Nigeria's First Lady, Aisha Buhari, has appointed Dolapo Osinbajo, the wife of the vice president of Nigeria, and wives of all governors of states across Nigeria as 'champions' to lead the fight against TB in Nigeria.
[The Conversation Africa] The infectious disease burden in Africa is very high, particularly for tuberculosis (TB), malaria and HIV/AIDS. In 2018, nearly a quarter (24%) of TB cases in the world were in Africa. The region accounted for 93% of malaria cases. The continent also bears the brunt of the HIV epidemic: 20.6 million of the 37.9 million people living with HIV are in eastern and southern Africa.
CONCLUSION: the rates of cure and abandonment are far from the ones recommended by the World Health Organization, showing that Brazilian capitals need interventions aimed at changing this pattern. PMID: 31826160 [PubMed - in process]
PMID: 31822236 [PubMed - in process]
Analyst, 2019, Accepted Manuscript DOI: 10.1039/C9AN01994D, PaperYan Li, Xiao-man Wu, Jun-hua Zhang, Zi-shuo Feng, Wen-xin Chen, Fei Zhang Rifampicin is a common antibiotic used as human and veterinary medicine to treat tuberculosis and the other diseases caused by numerous pathogenic bacteria. It usually leads to a series of... The content of this RSS Feed (c) The Royal Society of Chemistry