Streptococcus pneumoniae serotype 19A from carriers and invasive disease: virulence gene profile and pathogenicity in a Galleria mellonella model
ConclusionsThe occurrence of the investigated virulence genes was similar between HC and IPDS. pneumoniae serotype 19A groups. However, the IPD isolates showed a higher lethality in the alternativeG. mellonella model than the HC isolates, regardless of the virulence gene composition, indicating that other virulence factors may play a decisive role in virulence. Currently, this is the first report using the in vivoG. mellonella model to study the virulence of clinical isolates ofS. pneumoniae.