Mutation of FLNA attenuating the migration of abdominal muscles contributed to Melnick-Needles syndrome (MNS) in a family with recurrent miscarriage

CONCLUSION: Our research revealed a mutation site of the FLNA for MNS and explored the mechanism of midline structure dysplasia in the abdominal wall of male patients, which could provide more evidence for the clinical diagnosis and genetic counseling of families with these disorders.PMID:36734119 | DOI:10.1002/mgg3.2145

Source: Molecular Medicine - February 3, 2023 Category: Molecular Biology Authors: Xin Luo Zailin Yang Jing Zeng Jing Chen Ningxuan Chen Xiaoyan Jiang Qinlv Wei Ping Yi Jing Xu Source Type: research