Comparison of whole-body DW-MRI with 2-[ < sup > 18 < /sup > F]FDG PET for staging and treatment monitoring of children with Langerhans cell histiocytosis

CONCLUSION: Our study showed that WB DW-MRI has similar accuracy to 2-[18F]FDG PET for staging and treatment monitoring of LCH in children. While 2-[18F]FDG PET remains an approved radiological examination for assessing metabolically active disease, WB DW-MRI could be considered as an alternative approach without radiation exposure. The combination of both modalities might have advantages over either approach alone.PMID:36717409 | DOI:10.1007/s00259-023-06122-6

Source: Molecular Medicine - January 30, 2023 Category: Molecular Biology Authors: Lucia Baratto Ramyashree Nyalakonda Ashok J Theruvath Amir Hossein Sarrami Kristina Elizabeth Hawk Ali Rashidi Sa Shen Lisa States Mariam Aboian Michael Jeng Heike E Daldrup-Link Source Type: research