Effects of Systemic Drugs on the Development and Progression of Age-Related Macular Degeneration

Age-related macular degeneration (AMD) affects central vision and leads to a substantial loss of visual acuity. AMD involves mainly the central area of the retina. It may lead to an impairment of central vision and difficulty with dark adaptation via degenerative effects on the paracentral and more peripheral retina besides the central macula. The risk of AMD increases with age and is the leading cause of vision loss in the United States in people over the age of 60.[63,70] The pathophysiology of this disease is multifactorial: a combination of genetic, aging, inflammatory, and environmental factors.
Source: Survey of Ophthalmology - Category: Opthalmology Authors: Tags: Review article Source Type: research