Urine-based multi-omic comparative analysis of COVID-19 and bacterial sepsis-induced ARDS

CONCLUSION: In summary, our results provide evidence for significant molecular differences in ARDS patients from different etiologies and a potential synergy of extracellular matrix molecules, inflammation, and mitochondrial dysfunction in ARDS pathogenesis. The proteomic mortality signature should be further investigated in future studies to develop prediction models for COVID-19 patient outcomes.PMID:36703108 | DOI:10.1186/s10020-023-00609-6
Source: Molecular Medicine - Category: Molecular Biology Authors: Source Type: research