Interactive effects of a common γ-glutamyltransferase 1 variant and low high-density lipoprotein-cholesterol on diabetic macro- and micro-angiopathy
Conclusions:
We herein describe for the first time the significant interactive effects of the GGT1 G allele and a low HDL-C level on a high baPWV and DR. These findings may encourage future clinical trials comparing the efficacy of agents increasing the HDL-C levels among the GGT1 genotypes. However, well-designed studies in larger cohorts are needed to confirm our results.
Source: Cardiovascular Diabetology - Category: Cardiology Authors: Hideaki JinnouchiKazunori MoritaTakahiro TanakaAyami KajiwaraYuki KawataKentaro OnikiJunji SaruwatariKazuko NakagawaKoji OtakeYasuhiro OgataAkira YoshidaSeiji HokimotoHisao Ogawa Source Type: research
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