Targeting Glia to Treat Chronic Pain: Moving from Concept to Clinical Trials
Targeting Glia to Treat Chronic Pain: Moving from Concept to Clinical TrialsPresented by: Linda R. Watkins, PhD, Distinguished Professor, Department of Psychology and Neuroscience, University of Colorado at BoulderCategory: SpecialAired date: 05/04/2015
No abstract available
ConclusionsPamidronate is a safe and efficient method of CRMO therapy, particularly in cases refractory to NSAIDs treatment. Treatment with pamidronate provides both symptomatic relief as well as normalisation of bone morphology.
Publication date: Available online 16 June 2019Source: Joint Bone SpineAuthor(s): Pierre Letellier, Florian Bailly, Marina Assadourian, Antoine Potel, Violaine Foltz, Sophia Ascione, Laetitia Morardet, Myrianne Le Ralle, Bruno Fautrel, Arnaud Dupeyron, Nada Ibrahim-Nasser, Isabelle Griffoul-Espitalier, Bernard Duplan, Johann Beaudreuil, Laure Gossec
Condition: Chronic Low-back Pain Intervention: Other: acupuncture Sponsors: Wenzhou Medical University; Qingtian People's hospital Not yet recruiting
Did you know that tooth decay is the most common chronic disease of childhood? And that 40% of children have tooth decay by kindergarten? This is a big deal, not only because of the pain and infection it can cause, but also because children with tooth decay are more likely to miss school and have poorer grades — and because tooth decay is linked to a higher risk of many health problems later in life, including heart disease and premature birth. Tooth decay is simple to prevent, yet sadly, many families don’t take the steps that are needed. 1. Don’t skip the fluoride. Fluoride is very helpful w...
In the June 14thWall Street Journal, Johns Hopkins University bioethicist Travis Rieder, in an excellent essay, shared with readers his battle with pain resulting from a devastating accident, the effectiveness of opioids in controlling the pain, and the hell he went through when he was too rapidly tapered off of the opioids to which he had become physically dependent. Like most patients requiring long term pain management with opioids, he developed a physical dependence, which is often mistakenly equated with addiction by policymakers and many in the media. The aggressive schedule launched me into wit...
Learning is perceived as a process of personal and social construction where people are actively involved in making sense of information they interact with, rather than passively receiving it (Kuhthau 2004). This cumulative and developmental process involves the whole person in thinking, acting, reflecting, discovering ideas, making connections, and transforming prior knowledge, skills, attitudes, and values into new knowledge (Dewey 1933). I’m an educator for much of my time. When I think about it, I’ve been an educator for most of my clinical career – after all, when I helped people learn how to show...
Neuropsychopharmacology, Published online: 17 June 2019; doi:10.1038/s41386-019-0439-zSleep deficiency and chronic pain: potential underlying mechanisms and clinical implications
ConclusionsACC DBS may be a safe and promising surgical option to alleviate discomfort and improve the overall quality of life in a patient affected by drug-resistant TPS. Further prospective, larger, and randomized studies are needed to validate these findings.
In conclusion, for schoolchildren of higher elementary school grades, the risk of OSD is higher among girls with the epiphyseal stage. Cartilage thickness may not contribute to the diagnosis of OSD, since thick cartilage is not very common in OSD. However, cartilage thickness may reflect the status of OSD.