A complex heterozygous mutation in PADI6 causes early embryo arrest: A case report

Conclusion: We found a complex heterozygous mutation in the PADI6 gene (c. 1247T>C; c. 2009_2010del) that caused embryos were arrested at the 1- or 2- cell stage. The discovery in this patient adds to the evidence showing the PADI6 gene mutation causes early embryo arrest in humans.
Source: Frontiers in Genetics - Category: Genetics & Stem Cells Source Type: research