Comparative Efficacy of Interventions for Overactive Bladder Syndrome: A Systematic Review And Network Meta-Analysis

There is a plethora of interventions for the treatment of overactive bladder syndrome, including a course of supervised pelvic floor muscle training, behavioral therapy, anticholinergic medication, sacral nerve stimulation, and more recently, botulinum toxin type A (BoNT-A) and beta-3-adrenergic agonists. Though there is a large and diverse range of treatment options, there is little information of which of them is the most clinically effective. This is largely because trials often compare interventions with a placebo or with interventions of the same class; and so there are a limited number of trials that compare interventions of different classes, and thus different approaches on a head-to-head basis.

Source: Value in Health - May 1, 2015 Category: Global & Universal Authors: R.K. Owen, D.G. Tincello, S. Bujkiewicz, K. Abrams Tags: Urinary/Kidney Disorders – Clinical Outcomes Studies Source Type: research