The relation between prediction model performance measures and patient selection outcomes for proton therapy in head and neck cancer

CONCLUSIONS: Each measure independently impacts ΔNTCP and patient selection and should thus be assessed in a representative sufficiently large external sample. Our suggested practical model selection approach is considering the model with the highest AUC, and recalibrating it if needed.PMID:36566991 | DOI:10.1016/j.radonc.2022.109449

Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - December 25, 2022 Category: Radiology Authors: A M Leeuwenberg J B Reitsma L V D Bosch Jeroen Hoogland A V D Schaaf Frank J P Hoebers Oda B Wijers J A Langendijk K G M Moons E Schuit Source Type: research