Ribbon Synapses in Zebrafish Hair Cells.

Ribbon Synapses in Zebrafish Hair Cells.
Hear Res. 2015 Apr 24;
Authors: Nicolson T
Abstract
The basic architecture and functionality of ribbon synapses of mechanosensitive hair cells are well conserved among vertebrates. Forward and reverse genetic methods in zebrafish (Danio rerio) have identified components that are critical for the development and function of ribbon synapses. This review will focus on the findings of these genetic approaches, and discuss some emergent concepts on the role of the ribbon body and calcium in synapse development, and how perturbations in synaptic vesicles lead to a loss of temporal fidelity at ribbon synapses.
PMID: 25916266 [PubMed - as supplied by publisher]

Source: Hearing Research - April 24, 2015 Category: Audiology Authors: Nicolson T Tags: Hear Res Source Type: research