Cardiac amyloidosis —An underdiagnosed cause of heart failure: A case report and review of literature

Cardiac amyloidosis should be considered in patients with diastolic heart failure and nephrotic syndrome. Strain analysis is a specific finding. A high index of suspicion is required and early initiation of therapy improves outcomes. AbstractRestrictive cardiomyopathy secondary to cardiac amyloidosis is an underdiagnosed, but treatable, cause of heart failure involving an extracellular deposition of misfolded protein. Hereby, we report a case of a female patient with history of nephrotic syndrome for 1 year who subsequently presented with symptoms of heart failure. The findings on cardiac imaging supported the suspicion of cardiac amyloidosis. Further laboratory workup for amyloidosis was pursued along with endomyocardial biopsy which confirmed amyloidosis-AL type. Patient was started on chemotherapy. The case underscores the importance of a timely diagnosis with the help of symptomatology and imaging along with a multidisciplinary approach for patient care.

Source: Clinical Case Reports - December 3, 2022 Category: General Medicine Authors: Kanak Parmar, Juthipong Benjanuwattra, Pooja Sethi, Lukman Tijani, Philip Hurst, Gaspar Del ‐Rio Pertuz, Erwin Argueta‐Sosa Tags: CASE REPORT Source Type: research