Acute kidney injury: an acceptable risk of treatment with renin-angiotensin system blockade in primary care?

Conclusions Use of RAS antagonists increased the risk of AKI, independent of common confounding variables. After correction for confounders the risk fell away and became non-significant for moderate and severe AKI. However, where there was no evidence-based indication for RAS antagonists the risk of AKI, whether mild, moderate or severe, remained greater.
Source: Canadian Journal of Kidney Health and Disease - Category: Urology & Nephrology Source Type: research