Assessing Variability and Correlation between the SUV and ADC Parameters of Head and Neck Cancer Derived from Simultaneous PET/MRI: A Single Center Pilot Study in Thailand

Intratumoral heterogeneity is associated with poor outcomes in head and neck cancer patients due to chemoradiotherapy resistance. 18F FDG PET/MRI yields spatial information of tumor mass, allowing intratumor heterogeneity assessment through histogram analysis. However, the variability in quantitative PET/MRI parameters measurement could influence their reliability for assessment of patient prognosis. Therefore, as an initial step to utilizing standardized uptake value (SUV) and apparent diffusion coefficient (ADC) parameters for assessing tumor response, this study aims to measure SUV and ADC's variability and assess their relationship in head and neck cancers.

Source: Journal of Medical Imaging and Radiation Sciences - December 1, 2022 Category: Radiology Authors: P Wongsa, M Nantasuk, S Singhnoi, P Pawano, A Jantarato, D Siripongsatian, P Lerdsirisuk, M Phonlakrai Source Type: research