Evidence for a role of the aryl hydrocarbon receptor in inflammatory responses to air pollution

Conclusion: The AhR does not play a role in PM2.5 induced DC maturation. Whilst there is a clear, PM2.5 source dependent, CD4 T-cell proliferative and Th17 response, it remains unclear whether PM associated PAHs contribute to these responses.

Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: Glencross, D., Cheadle, C., Palaga, T., Prueksasit, T., Lertmemongkolchai, G., Mudway, I., Hawrylowicz, C. Tags: 03.02 - Airway cell biology and immunopathology Source Type: research