Functional improvement in individuals with chronic spinal cord injury treated with 4-aminopyridine: A systematic review

ConclusionsThis review confirms the efficacy of 4-AP in improving several conditions resulting from SCI but further research on this topic is warranted. Additional randomized clinical trials with 4-AP involving larger sample sizes are needed, as are consistent outcome measures in order to obtain adequate data for analysis with a view to enhance treatment benefits.Systematic review registration, PROSPERO CRD42022334835.
Source: Frontiers in Neurology - Category: Neurology Source Type: research