Study Illuminates Nodal Failure After Cervix Cancer TherapyStudy Illuminates Nodal Failure After Cervix Cancer Therapy

Current therapy for cervical cancer results in high local control rates and acceptable morbidity, but if patients develop a nodal failure, survival is poor. Medscape Medical News
Source: Medscape Hematology-Oncology Headlines - Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

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In conclusion, combining MMC with NE-based ESSOs has increased the cytotoxic effect of the MMC on the HeLa cells with different mechanism of actions.Graphical abstract
Source: Chemico Biological Interactions - Category: Biochemistry Source Type: research
Publication date: August 2018Source: Gynecologic Oncology Reports, Volume 25Author(s): Bryan J. Ager, Dolores Gallardo-Rincón, David Cantú de León, Adriana Chávez-Blanco, Linus Chuang, Alfonso Dueñas-González, Eva Gómez-García, Roberto Jerez, Anuja Jhingran, Mary McCormack, Linda Mileshkin, Carlos Pérez-Plasencia, Marie Plante, Andrés Poveda, David K. GaffneyAbstractCervical cancer is the fourth most common cancer in women with 85% of the mortality burden occurring in less-developed regions of the world. The Cervix Cancer Research Network (CCRN) was foun...
Source: Gynecologic Oncology Reports - Category: OBGYN Source Type: research
In conclusion, combining MMC with NE-based ESSOs has increased the cytotoxic effect of the MMC on the HeLa cells with different mechanism of actions.Graphical abstract
Source: Chemico Biological Interactions - Category: Biochemistry Source Type: research
Publication date: August 2018Source: Gynecologic Oncology Reports, Volume 25Author(s): Bryan J. Ager, Dolores Gallardo-Rincón, David Cantú de León, Adriana Chávez-Blanco, Linus Chuang, Alfonso Dueñas-González, Eva Gómez-García, Roberto Jerez, Anuja Jhingran, Mary McCormack, Linda Mileshkin, Carlos Pérez-Plasencia, Marie Plante, Andrés Poveda, David K. GaffneyAbstractCervical cancer is the fourth most common cancer in women with 85% of the mortality burden occurring in less-developed regions of the world. The Cervix Cancer Research Network (CCRN) was foun...
Source: Gynecologic Oncology Reports - Category: OBGYN Source Type: research
Authors: Qu X, Gao D, Ren Q, Jiang X, Bai J, Sheng L Abstract Cervical cancer remains one of the most frequent gynecological malignancies among females around the world. Therefore, fully understanding the molecular mechanisms underlying the progression of cervical cancer may be critical for the development of effective therapeutic strategies against cervical cancer. The object was to evaluate the potential effect of miR-211 and verify its influence on the function of secreted protein acidic and rich in cysteine (SPARC) in cervical cancer. It was demonstrated that miR-211 was downregulated in cervical cancer cell li...
Source: Oncology Letters - Category: Cancer & Oncology Tags: Oncol Lett Source Type: research
In conclusion, combining MMC with NE-based ESSOs has increased the cytotoxic effect of the MMC on the HeLa cells with different mechanism of actions. Graphical abstract
Source: Chemico Biological Interactions - Category: Biochemistry Source Type: research
SummaryKinases and phosphatases are important players in growth signaling and are involved in cancer development. For development of targeted cancer therapy, attention is given to kinases rather than phosphatases inhibitors. Src homology region 2 domain-containing protein tyrosine phosphatase2 (SHP2) is overexpressed in different types of cancers. We investigated the SHP2-inhibitory effects of two new 5-aminosalicylate –4-thiazolinones in human cervical (HeLa) and breast (MCF-7&MDA-MB-231) cancer cells.In-silico molecular docking showed preferential affinity of the two compounds towards the catalytic over the all...
Source: Investigational New Drugs - Category: Drugs & Pharmacology Source Type: research
Conclusion: These findings shed light on the mechanisms of GO/CDDP-induced chemosensitization and implicate the potential applications of GO/CDDP to treat multiple cancers.
Source: Theranostics - Category: Molecular Biology Authors: Tags: Research Paper Source Type: research
Publication date: Available online 12 June 2018 Source:Gynecologic Oncology Reports Author(s): Bryan J. Ager, Dolores Gallardo-Rincón, David Cantú de León, Adriana Chávez-Blanco, Linus Chuang, Alfonso Dueñas-González, Eva Gómez-García, Roberto Jerez, Anuja Jhingran, Mary McCormack, Linda Mileshkin, Carlos Pérez-Plasencia, Marie Plante, Andrés Poveda, David K. Gaffney Cervical cancer is the fourth most common cancer in women with 85% of the mortality burden occurring in less-developed regions of the world. The Cervix Cancer Research Network (CCRN) was fo...
Source: Gynecologic Oncology Reports - Category: OBGYN Source Type: research
In conclusion, combining MMC with NE-based ESSOs has increased the cytotoxic effect of the MMC on the HeLa cells with different mechanism of actions. PMID: 29908166 [PubMed - as supplied by publisher]
Source: Chemico-Biological Interactions - Category: Molecular Biology Authors: Tags: Chem Biol Interact Source Type: research
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