Do common infections trigger disease-onset or -severity in CTLA-4 insufficiency?

CONCLUSIONS: Our results show that the investigated pathogens are very unlikely to trigger the disease onset in CTLA-4-insufficient individuals, and their prevalence is not correlated with disease severity or expressivity.PMID:36405723 | PMC:PMC9667032 | DOI:10.3389/fimmu.2022.1011646

Source: Herpes - November 21, 2022 Category: Infectious Diseases Authors: M áté Krausz Noriko Mitsuiki Valeria Falcone Johanna Komp Sara Posadas-Cantera Hanns-Martin Lorenz Jiri Litzman Daniel Wolff Maria Kanariou Anita Heinkele Carsten Speckmann Georg H äcker Hartmut Hengel Laura G ámez-Díaz Bodo Grimbacher Source Type: research