Investigation of the effects of opioids on microglial nitrite and nitric oxide synthase (iNOS) production and phagocytosis during inflammation

CONCLUSION: Buprenorphine and salvinorin A were found to reduce NO production and iNOS induction in microglial cells activated by LPS and IFN-γ. Salvinorin A promoted the phagocytosis of microglia cells treated by LPS.PMID:36372918 | DOI:10.2174/1386207326666221111093915
Source: Combinatorial Chemistry and High Throughput Screening - Category: Chemistry Authors: Source Type: research