Dysregulation of male sex hormones in chronic hepatitis C patients

This study aimed at estimation of a panel of the most important related hormones in the serum of patients and illustration of their correlation to the routine laboratory investigations. The four studied hormones showed alteration in the patients in comparison with the controls. While androstenedione, prolactin and testosterone were significantly increased in patients, dehydroepiandrosterone sulphate was decreased. These changes in the hormones were not related to the liver functions, pathological grade or even viral load. We hypothesised a model of how HCV can induce these hormonal changes and recommended to add these hormones to the follow‐up panel of male patients with HCV.
Source: Andrologia - Category: Urology & Nephrology Authors: Tags: Original Article Source Type: research