IJERPH, Vol. 19, Pages 14451: Mesonephric-Like Adenocarcinomas a Rare Tumor: The Importance of Diagnosis

IJERPH, Vol. 19, Pages 14451: Mesonephric-Like Adenocarcinomas a Rare Tumor: The Importance of Diagnosis International Journal of Environmental Research and Public Health doi: 10.3390/ijerph192114451 Authors: Stefano Restaino Giulia Pellecchia Angelica Tulisso Chiara Paglietti Maria Orsaria Claudia Andreetta Elena Poletto Martina Arcieri Monica della Martina Anna Biasioli Laura Mariuzzi Lorenza Driul Giovanni Scambia Giuseppe Vizzielli Mesonephric-like adenocarcinomas (MLA) are rare neoplasms that arise in the uterine body and ovary and have been added to the World Health Organisation’s recent 2020 classification of female genital cancers. The pathogenesis of MLA is unknown and it remains debated whether they represent mesonephric carcinomas (Wolffian) arising in the endometrium/ovary or endometrioid carcinomas (Müllerian) closely mimicking mesonephric carcinomas. Here we report the case of a 57-year-old woman with an initial misdiagnosis of endometrioid adenocarcinoma on diagnostic biopsy. The patient came to our clinical evaluation for the appearance of menometrorrhagia complicated by anemia for several months. Therefore, she underwent pelvic echo-flowmetry, with indication for diagnostic hysteroscopy with endometrial biopsy, which yielded a positive result for endometrioid endometrial adenocarcinoma. Following staging CT scan and targeted examinations on pulmonary findings, the patient underwent surgery with surp...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Case Report Source Type: research