Targeting Inflammasomes in Substance Abuse and HIV (R01 Clinical Trial Not Allowed)

Funding Opportunity RFA-DA-24-003 from the NIH Guide for Grants and Contracts. The scientific objective of this Funding Opportunity Announcement is to encourage research to delineate the role of inflammasomes in the neuropathology produced by acute or chronic drug exposure and HIV infection. Understanding the involvement of inflammasomes in virus and drug-induced immune activation may help identify molecular markers and CNS immune cells associated with HIV-1 infection or disease progression among substance abuse populations, as well as identify novel therapies to target inflammasome activation or suppression to treat neuroinflammation and immune dysregulation aroused in these processes.
Source: NIH Funding Opportunities (Notices, PA, RFA) - Category: Research Source Type: funding