Overexpression of BDNF and Full-Length TrkB Receptor Ameliorate Striatal Neural Survival in Huntington's Disease.

CONCLUSION: The results highlight the importance of BDNF-induced TrkB receptor signaling in rescuing HD-mediated apoptotic features in striatal cells. © 2015 S. Karger AG, Basel.
PMID: 25896770 [PubMed - as supplied by publisher]

Source: Neuro-Degenerative Diseases - April 21, 2015 Category: Neurology Authors: Silva A, Naia L, Dominguez A, Ribeiro M, Rodrigues J, Vieira OV, Lessmann V, Rego AC Tags: Neurodegener Dis Source Type: research