Impaired platelet function and thrombus formation in PDE5A-deficient mice

In conclusion, PDE5A modulates platelet activation, function and thrombus formation, indicating that therapeutic targeting it might be beneficial for the treatment of thrombotic diseases.PMID:36252813 | DOI:10.1055/a-1962-1613

Source: Thrombosis and Haemostasis - October 17, 2022 Category: Hematology Authors: Xiang Gui Xiang Chu Yuwei Du Yuhan Wang Sixuan Zhang Yangyang Ding Huan Tong Mengdi Xu Yue Li Wen Ju Zengtian Sun Zhenyu Li Lingyu Zeng Kailin Xu Jianlin Qiao Source Type: research