Selective human factor VIII activity measurement after analytical in-line purification
CONCLUSION: Combining antibody-mediated specific capture of human FVIII and a chromogenic activity assay resulted in a selective and sensitive measurement of human FVIII with no interference by endogenous, nonhuman FVIII, manufacturing process additives, or an FVIII activity-mimicking antibody.PMID:36254254 | PMC:PMC9561358 | DOI:10.1002/rth2.12821
Source: Thrombosis and Haemostasis - Category: Hematology Authors: Andrea Engelmaier Gerald Schrenk Manfred Billwein Herbert Gritsch Christoph Zlabinger Alfred Weber Source Type: research