Acquired hemophilia following COVID-19 vaccination: Case report and review of literature

CONCLUSIONS: The diagnosis of AHA with a relapse of bullous pemphigoid was made. The patient was treated with recombinant activated factor VII, emicizumab, rituximab, and methylprednisolone. There were no further bleeding events. However, the patient deteriorated because of sepsis and died on the fifteenth day of admission.CONCLUSION: Vaccines may trigger autoimmune events such as AHA. However, proof of causality is not possible and in this case the relapse of bullous pemphigoid before vaccination challenges this even more.PMID:36176309 | PMC:PMC9459413 | DOI:10.1002/rth2.12785
Source: Thrombosis and Haemostasis - Category: Hematology Authors: Source Type: research