Vitamin D and interferon- γ co-operate to increase the ACE-2 receptor expression in primary cultures of human thyroid cells

ConclusionsVitD would defend the body by SARS-COV2 both by regulating the host immune defense and by up-regulating of the expression of the ACE-2 receptor. The existence of a co-operation between VitD and IFN- γ demonstrated in other systems is supported also for ACE-2 up-regulation. These observations lead to an increased interest for the potential therapeutic benefits of VitD supplementation in COVID-19.
Source: Journal of Endocrinological Investigation - Category: Endocrinology Source Type: research