Circ_0021155 can participate in the phenotypic transformation of human vascular smooth muscle cells via the miR-4459/TRPM7 axis

In conclusion, hsa_circ_0021155 regulates the proliferation, migration and phenotype transformation of VSMCs induced by OX-LDL via the miR-4459/TRPM7 axis. hsa_circ_0021155 and TRPM7 may offer novel therapeutic targets for atherosclerosis.PMID:36155059 | DOI:10.1016/j.bbrc.2022.08.065

Source: Atherosclerosis - September 26, 2022 Category: Cardiology Authors: Jinghan Lin Chang Liu Jing Xu Shuang Li Dawei Dai Liming Zhang Pan Yonghui Source Type: research