Mammalian Sterile 20-Like Kinase 1 Suppresses Atherosclerosis

CONCLUSIONS: Our study reveals that inhibition of the MST1-Cx43 axis is an essential driver of oscillatory shear stress-induced endothelial dysfunction and atherosclerosis, which provides a new therapeutic target for the treatment of atherosclerosis.PMID:36164986 | DOI:10.1161/CIRCRESAHA.122.321322

Source: Atherosclerosis - September 27, 2022 Category: Cardiology Authors: Meixi Quan Huizhen Lv Zening Liu Kan Li Chenghu Zhang Lei Shi XinYu Yang Ping Lei Yi Zhu Ding Ai Source Type: research