Thrombosis and thromboembolism: Brighton collaboration case definition and guidelines for data collection, analysis, and presentation of immunization safety data

Vaccine. 2022 Sep 20:S0264-410X(22)01085-4. doi: 10.1016/j.vaccine.2022.09.001. Online ahead of print.ABSTRACTThis is a Brighton Collaboration case definition of thrombosis and thromboembolism to be used in the evaluation of adverse events following immunization, and for epidemiologic studies for the assessment of background incidence or hypothesis testing. The case definition was developed by a group of experts convened by the Coalition for Epidemic Preparedness Innovations (CEPI) in the context of active development of SARS-CoV-2 vaccines. The case definition format of the Brighton Collaboration was followed to develop a consensus definition and defined levels of certainty, after an exhaustive review of the literature and expert consultation. The document underwent peer review by the Brighton Collaboration Network and by selected expert reviewers prior to submission.PMID:36150973 | DOI:10.1016/j.vaccine.2022.09.001

Source: Vaccine - September 23, 2022 Category: Allergy & Immunology Authors: Jahnavi Gollamudi Sarah E Sartain Amir Hassan Navaei Satinder Aneja Pawandeep Kaur Dhawan Dat Tran Jyoti Joshi Jane Gidudu Jayakrishna Gollamudi Elena Chiappini Frederick Varricchio Barbara Law Flor M Munoz Source Type: research