Alkaline Phosphatase, Bilirubin Levels and Outcomes in PBCAlkaline Phosphatase, Bilirubin Levels and Outcomes in PBC

Do alkaline phosphatase and bilirubin levels help clinicians predict disease outcome in patients with primary biliary cirrhosis? Gastroenterology
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

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Conclusions: Multiple risk factors for rALDs were identified, such as colectomy before LT, cholangiocacinoma, multiple episodes of acute cellular rejection, model for end-stage liver disease score, and especially the use of mycophenolate mofetil, cyclosporin A and tacrolimus.
Source: Medicine - Category: Internal Medicine Tags: Research Article: Systematic Review and Meta-Analysis Source Type: research
We describe a relatively young cirrhotic woman who developed splenic infarctions in the setting of alcoholic hepatitis. PMID: 32313472 [PubMed]
Source: Baylor University Medical Center Proceedings - Category: Universities & Medical Training Authors: Tags: Proc (Bayl Univ Med Cent) Source Type: research
We describe the case of a 50-year-old female patient with class II obesity and primary biliary cirrhosis, evaluated for mixed dyslipidemia with poor control (statins and fibrates were being administered) as well as abnormal liver tests. The investigation carried out revealed primary auto-immune hypothyroidism. After normalisation of thyroid function by treatment with levothyroxine, as well as suspending the administration of statins and fibrates, there was an improvement in the lipid profile, although hypercholesterolemia continued. During this time, the patient was diagnosed with diabetes and she re-commenced statin thera...
Source: Acta Medica Portuguesa - Category: General Medicine Tags: Acta Med Port Source Type: research
No abstract available
Source: Gastroenterology Nursing - Category: Nursing Tags: Departments: Clinical Case Study Source Type: research
ConclusionsThere are differences in ANA positivity among patients with SARD and various liver diseases. Some mixed patterns may provide important evidence for the diagnosis of PBC. Clinicians should pay attention to ANA patterns and titer during the interpretation of this test.Key Points• Defining the clinical relevance of antinuclear antibody (ANA) using indirect immunofluorescence assay in the context of diseases can be an important tool for the clinician in the diagnostic work-up of patients with liver diseases.• The mixed pattern of ANA is majorly found in primary biliary cirrhosis (PBC). ANA patterns includi...
Source: Clinical Rheumatology - Category: Rheumatology Source Type: research
Conclusions: The fact that high levels of AMA in the 6 patients were all associated with mold and moisture exposure appears to be significant. Exposure to water- and mold-damaged indoor environments might damage mitochondria and trigger autoimmunity. Long term follow-up is needed to determine what may develop in these patients. PMID: 32088666 [PubMed - as supplied by publisher]
Source: Alternative Therapies in Health and Medicine - Category: Complementary Medicine Authors: Tags: Altern Ther Health Med Source Type: research
Condition:   Primary Biliary Cirrhosis Interventions:   Drug: TQA3526;   Drug: Placebo to match TQA3526 Sponsor:   Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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