Fracture Risk in Pediatric Patients with MEN2B

CONCLUSION: In this group of patients with MEN2B, there was an increased overall risk of fracture compared to general pediatric cohorts in the United States. Less common sites of fracture were also observed. This suggests a possible impact of an activating RET mutation on bone physiology and warrants further investigation.PMID:36056624 | DOI:10.1210/clinem/dgac500

Source: The Journal of Clinical Endocrinology and Metabolism - September 3, 2022 Category: Endocrinology Authors: Iris Li Iris R Hartley Joanna Klubo-Gwiedzdzinska James C Reynolds Barbara J Thomas Julie Hogan Mahider M Enyew Eva Dombi Alexander Ling Srivandana Akshintala David J Venzon Jaydira Del Rivero Michael Collins John W Glod Source Type: research