Clinical features of subclinical left ventricular systolic dysfunction in patients with diabetes mellitus
Background:
Left ventricular (LV) longitudinal systolic dysfunction has been identified even in asymptomatic patients with diabetes mellitus (DM) and preserved LV ejection fraction (LVEF). However, its relevant clinical features have not been fully evaluated.
Methods:
We studied 144 asymptomatic DM patients without coronary artery disease. Their mean age was 57 ± 15 years, 79 (55%) were female, and mean LVEF was 66 ± 4% (all ≥50%). Global longitudinal strain (GLS) was determined as the average peak strain of 18 segments from the three standard apical views, and was expressed as an absolute value. With the pre-defined cutoff for subclinical LV systolic dysfunction in DM patients with preserved LVEF set at GLS
Source: Cardiovascular Diabetology - Category: Cardiology Authors: Yasuhide MochizukiHidekazu TanakaKensuke MatsumotoHiroyuki SanoHiromi TokiHiroyuki ShimouraJunichi OokaTakuma SawaYoshiki MotojiKeiko RyoYushi HirotaWataru OgawaKen-ichi Hirata Source Type: research