Eye disorders in newborn infants (excluding retinopathy of prematurity)

A screening eye examination is an essential part of the newborn assessment. The detection of many ocular disorders in newborn infants can be achieved through careful observation of the infant's visual behaviour and the use of a direct ophthalmoscope to assess the ocular structures and check the red reflex. Early diagnosis and subspecialty referral can have a critical impact on the prognosis for many ocular conditions, including potentially blinding but treatable conditions such as congenital cataracts, life-threatening malignancies such as retinoblastoma and harbingers of disease elsewhere such as sporadic aniridia and its association with the development of Wilms tumour.
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - Category: Perinatology & Neonatology Authors: Tags: Reviews Source Type: research

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Publication date: June 2020Source: Parasitology International, Volume 76Author(s): A.C. Campello, L.G.F.A.B.D.E. Zanella, R.B. Suzuki, M.O. Tokumo, E.F.B. Chagas, W. Baleotti, M.A. Sperança, L.P.A. MartinsAbstractTrypanosoma cruzi infection triggers an intense production of pro-inflammatory cytokines mediated by T helper 1 lymphocytes, inducing the anti-inflammatory reflex of acetylcholine (ACh). The ACh concentration modulation is associated to the two major esterases, the acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE). AChE H353N protein polymorphism is related to low Chagas chronic disease prognost...
Source: Parasitology International - Category: Parasitology Source Type: research
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Source: Eye and Contact Lens: Science and Clinical Practice - Category: Opthalmology Tags: Erratum Source Type: research
Conclusion: This is the first case series of toxic posterior segment syndrome occurring secondary to intracameral compounded triamcinolone-moxifloxacin in dropless cataract surgery. The FDA has attributed the toxicity to abnormally high levels of the binding agent poloxamer 407 in the compounded medication. Clinicians should be aware of this phenomenon and exhibit caution when using compounded medications.
Source: RETINA - Category: Opthalmology Tags: Original Study Source Type: research
Conclusion: The findings support the notion of a progression of a ridge-shaped macula parallel to a further deepening of a macular suprachoroidal cavitation in an axially elongating eye.
Source: RETINA - Category: Opthalmology Tags: Original Study Source Type: research
Publication date: April 2020Source: Cancer Epidemiology, Volume 65Author(s): Julie Volk, Julia E. Heck, Kjeld Schmiegelow, Johnni HansenAbstractBackgroundParental occupational exposures are suggested as contributing causes of childhood cancer.MethodsChildren age
Source: Cancer Epidemiology - Category: Cancer & Oncology Source Type: research
Vestibular failure or hypofunction can be generated by pathologies such as vestibular neuritis (VN), causing the onset of rotatory vertigo and the vestibulo-ocular reflex (VOR) hyporeaction. VN is a post-viral inflammation-producing vestibular nerve-axon impairment, which reaches compensation in 70% of cases. Here, we present two cases of vestibular failure that did not respond to pharmacological therapy, but did show modulated vestibular response after an osteopathic manipulative treatment. Dizziness handicap inventory (DHI) was used to assess disability, while VOR was examined by means of video head impulse test (v-HIT).
Source: Journal of Bodywork and Movement Therapies - Category: Physiotherapy Authors: Tags: Fascia Science and Clinical Applications Source Type: research
Multi-photon intravital microscopy (MP-IVM) is a powerful tool to image cells in vivo. Its application in immunology research has opened new horizons, allowing intravital imaging of leukocytes at the single cell level. A transparent cornea is vital to retain vision. As an immune privileged site, a quick innate response to foreign antigens is crucial in clearing opportunistic bacterial and viral pathogens and minimizing collateral structural damage to the cornea. Further, dissecting the mechanisms and preventing the rejection process after corneal transplantation is imperative to retain sight. Therefore, understanding the u...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
ConclusionOur findings suggest that consumption of a cafeteria diet increases sympathetic drive to the heart but not to the blood vessels, independent of impairment in baroreflex and chemoreflex functions. Other mechanisms may be involved in the increased cardiac sympathetic drive, and compensatory vascular mechanisms may prevent the development of hypertension in this model of obesity.
Source: Nutrition, Metabolism and Cardiovascular Diseases - Category: Nutrition Source Type: research
Leukocoria, also known as white puppilary reflex, is a symptom of a number of diseases, including retinoblastoma, Coats’ disease, and congenital cataracts. When light enters the eye at certain angles in people with leukocoria, a white reflectio...
Source: Medgadget - Category: Medical Devices Authors: Tags: Ophthalmology Pediatrics Source Type: blogs
Discussion Inflammation of the middle layer of the eye, or uvea, is termed uveitis. Uveitis can be divided into anterior, intermediate or posterior uveitis by involving the anterior (iris and ciliary body), intermediate (vitreous) or posterior (choroid and usually retina) compartments. Panuveitis involves all 3 compartments. Duration can also be used to classify uveitis. Acute is 6 weeks and> 3 months is chronic persistent uveitis. Episodic periods of inactivity and reactivity that last more than 3 months are called recurrent uveitis. A third way to characterize uveitis is if it is granulomatous or not. Uveitis increase...
Source: PediatricEducation.org - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news
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