Metformin-induced lactic acidosis : Severe symptoms with difficult diagnostics.

[Metformin-induced lactic acidosis : Severe symptoms with difficult diagnostics]. Anaesthesist. 2015 Apr 14; Authors: Decker SO, Wortmann M, Siegler BH, Ulrich A, Hofer S, Brenner T Abstract Metformin-induced lactic acidosis is a rare but severe disease for the individual patients. A case of a 64-year-old patient with diabetes mellitus type 2 suffering from this disease is presented where metformin accumulation was caused by prerenal acute kidney failure. The clinical evaluation up to the final diagnosis, the pathophysiology and the appropriate therapy are presented in detail. Additionally, the current guidelines regarding the perioperative management of metformin administration are summarized. The case described aims to direct attention to the rare but, nevertheless, severe symptoms of metformin-induced lactic acidosis. PMID: 25870002 [PubMed - as supplied by publisher]
Source: Der Anaesthesist - Category: Anesthesiology Authors: Tags: Anaesthesist Source Type: research

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