In vivo assessment of cardiac metabolism and function in the abdominal aortic banding model of compensated cardiac hypertrophy
Conclusion
Hypertrophied hearts revealed little evidence of a switch towards increased glucose oxidation but rather an uncoupling of glycolytic metabolism from glucose oxidation. This was maintained under conditions of dietary stress provided by a WD but, at this compensated phase of hypertrophy, did not result in any contractile dysfunction.
Source: Cardiovascular Research - Category: Cardiology Authors: Seymour, A.-M. L., Giles, L., Ball, V., Miller, J. J., Clarke, K., Carr, C. A., Tyler, D. J. Tags: Cardiac biology and remodelling Source Type: research
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