Comprehensive analyses of transcriptomes induced by Lyme spirochete infection to CNS model system

CONCLUSION: Our study suggested that TLR6, ANGPT1, LDLR, SREBF1, TNC, and ITGA may be candidate mammal biomarkers for LNB, and the TLR6/PI3K-Akt signaling pathway may play an important role in LNB pathogenesis.PMID:35964914 | DOI:10.1016/j.meegid.2022.105349

Source: Infection, Genetics and Evolution - August 14, 2022 Category: Genetics & Stem Cells Authors: Shiyuan Wen Xin Xu Jing Kong Lisha Luo Peng Yue Wenjing Cao Yu Zhang Meixiao Liu Yuxin Fan Jingjing Chen Mingbiao Ma Lvyan Tao Yun Peng Feng Wang Yan Dong Bingxue Li Suyi Luo Guozhong Zhou Taigui Chen Lianbao Li Aihua Liu Fukai Bao Source Type: research