Pleural thickening induced by Glaesserella parasuis infection was linked to increased collagen and elastin

In this study, pleural thickening was discovered to be associated with increased collagen fibers and elastic fibers. Furthermore, collagen-I and elastin were found to be up-regulated and concentrated in the pleura at the mRNA and protein levels following infection. To summarize, our findings add to the theoretical understanding of Glässer’s disease and provide strong support for further research into the pathogenic mechanism of Glaesserella parasuis and the program’s target treatment.

Source: Frontiers in cellular and infection microbiology - August 11, 2022 Category: Microbiology Source Type: research