How does age determine the development of human immune-mediated arthritis?

Nature Reviews Rheumatology, Published online: 10 August 2022; doi:10.1038/s41584-022-00814-3In this Review, the authors discuss age-related arthropathy and the similarities and differences between childhood loss of immune tolerance and adult development of immune-mediated arthritis, and develop three hypotheses describing age-related mechanisms that contribute to the onset of arthritis.

Source: Nature Reviews Rheumatology - August 10, 2022 Category: Rheumatology Authors: Yannick Degboe Sebastiaan J. Vastert Berent J. Prakken Iain B. McInnes Source Type: research