Breath test shows promise in diagnosing stomach cancer

Conclusion This is a useful proof of concept study that has demonstrated how the measurement of VOCs in exhaled breath may be of use in distinguishing different stages of pre-cancerous change from established stomach cancer. The researchers show that the new nanoarray system that looks at the pattern of VOCs in exhaled breath has high accuracy for distinguishing cancer from pre-cancer. However, it was less reliable at distinguishing between different stages of pre-cancer. The researchers suggest possible benefits of the nanoarray system in that it is non-invasive, quick, easy to use and inexpensive. They suggest that it could potentially provide a new method of screening for stomach cancer and pre-cancer, allowing a method of surveillance of people with pre-cancer who may be at different levels of risk for developing cancer in the future. However, this is too early to say whether this will come to fruition.  So far, this study has only examined the breath analyser in a sample of people with known diagnostic status. It would next need to be tested in samples of people with stomach symptoms and no established diagnosis, to see how accurate it was at indicating the diagnosis. It would also need to show whether it offers any benefits compared to current diagnostic methods. Stomach cancer is not currently screened for in the UK. Even if further study confirms that this test is reliable, the balance of benefits against risks need to be carefully considered before thinking abou...
Source: NHS News Feed - Category: Consumer Health News Tags: Cancer Medical practice Source Type: news

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This study evaluated pain incidence and characteristics of patients with pain after gastric ESD.MethodsWe retrospectively analyzed a prospectively collected registry of clinical, endoscopic, and pathologic results of patients who underwent ESD for gastric adenoma or cancer from January 2010 to December 2015. A Visual Analogue Scale (VAS) was used to assess pain immediately after, and 2, 12, and 24  h after ESD. The primary outcome was the use of painkillers (VAS score >  4). Analyzed data included age, sex, pathology, specimen and tumor size, procedure time, and tumor location.ResultsOf 1226 patients,...
Source: Surgical Endoscopy - Category: Surgery Source Type: research
BY KATHRYN M. DEPRIMO &KHALID MALIK, MDA 30-year-old man with no previous medical history presented with one day of epigastric pain, nausea, and vomiting. He described the pain as moderate, aching, and nonradiating. He said Tylenol provided minimal relief.The patient reported vomiting four or five times since the start of his symptoms and described the vomit as yellow in color. He had no history of recent travel, recent sick contacts, trauma, pain with eating, fever, chills, shortness of breath, chest pain, headaches, dizziness, changes in bowel movements, or urination. The patient confirmed a past surgical histor...
Source: The Case Files - Category: Emergency Medicine Tags: Blog Posts Source Type: research
This study identifies the missing link between Lewy bodies and the type of damage that's been observed in neurons affected by Parkinson's. Parkinson's is a disorder of the mitochondria, and we discovered how Lewy bodies are releasing a partial break-down product that has a high tropism for the mitochondria and destroys their ability to produce energy." Lewy bodies were described a century ago, but it was not until 1997 that scientists discovered they were made of clumps of a misfolded protein called α-synuclein. When it's not misfolded, α-synuclein is believed to carry out functions related to the ...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
The objective is to wind up with the right amount of FOXO4-DRI dissolved in phosphate buffered saline in a sealed vial, ready to be used with the injection system, and with as little contamination as possible from the environment. Depending on the size of the vial, it might contain doses for multiple injections - in fact it is much easier to set things up this way. FOXO4-DRI dissolves very readily in saline, so placing a single human dose into 0.5ml or 1ml is quite feasible. A 3ml vial can hold three doses for the treatment without issue. One approach is to measure out FOXO4-DRI by weight using a suitable microscale...
Source: Fight Aging! - Category: Research Authors: Tags: Self-Experimentation Source Type: blogs
When I was in South Africa last year, I met a revolutionary winemaker… His wine was completely organic. It had no toxins, and it contained powerful antioxidant properties. It was infused with a local herb called rooibos, also known as “red bush.” You may have seen rooibos tea on supermarket shelves. I immediately knew this wine should be made widely available in America — and I’m still hopeful a distributor will bring it here. I enjoy a nice glass of red wine from time to time, but the trouble with most of the wines sold in America is that they’re loaded with dangerous chemicals. Winema...
Source: Al Sears, MD Natural Remedies - Category: Complementary Medicine Authors: Tags: Health additives natural organic Sulfites wine Source Type: news
ConclusionsMechanisms connecting depression to physical illness appear to involve alterations in the hypothalamic‐pituitary axis, unhealthy lifestyle, chronic or acute stressors including posttraumatic stress, an increase in C‐reactive protein (CRP) in men, taking antidepressant medication, and social and emotional loneliness. Clinical RelevanceA good patient–provider relationship can help to promote decreased acute or chronic stressors, increased family and social support, decreased loneliness, modification of unhealthy lifestyles such as smoking, obesity, physical inactivity, alcohol, control of CRP, and antide...
Source: Journal of Nursing Scholarship - Category: Nursing Authors: Tags: CLINICAL SCHOLARSHIP Source Type: research
ConclusionsMechanisms connecting depression to physical illness appear to involve alterations in the hypothalamic‐pituitary axis, unhealthy lifestyle, chronic or acute stressors including posttraumatic stress, an increase in C‐reactive protein (CRP) in men, taking antidepressant medication, and social and emotional loneliness. Clinical RelevanceA good patient–provider relationship can help to promote decreased acute or chronic stressors, increased family and social support, decreased loneliness, modification of unhealthy lifestyles such as smoking, obesity, physical inactivity, alcohol, control of CRP, and antide...
Source: Journal of Nursing Scholarship - Category: Nursing Authors: Tags: CLINICAL SCHOLARSHIP Source Type: research
Conclusion. A review of the literature suggests that there are adequate data supporting the efficacy and general safety of the low-dose use of trazodone for the treatment of insomnia. keywords: insomnia, hypnotics, treatment, trazodone, sedative Keywords: insomnia, hypnotics, treatment, trazodone, sedative Innov Clin Neurosci. 2017;14(9–10):24–34 Introduction Insomnia is characterized by difficulty falling asleep, difficulty staying asleep, or waking too early1 and is associated with significant impairments in daytime activities, which might occur despite adequate opportunities for sleep.2–6 Primary insom...
Source: Innovations in Clinical Neuroscience - Category: Neuroscience Authors: Tags: Current Issue Review hypnotics insomnia sedative trazodone treatment Source Type: research
Conclusion This valuable cohort study helps to quantify the extent of bleeding risk in people taking aspirin for secondary prevention of cardiovascular disease. Aspirin is well known to carry bleeding risk – particularly in older adults – but this study suggests the risk may be higher than previously thought. The researchers say that for adults under the age of 75, the annual bleeding risk at around 1% is similar to that suggested by previous trials, as is the ratio of bleeds to the number of cardiovascular events. However, this risk increases for older adults, especially for major bleeds of the stomach and upp...
Source: NHS News Feed - Category: Consumer Health News Tags: Medication Older people Source Type: news
Abstract Currently, several types of amino acids are being produced and used worldwide. Nevertheless, several new functions of amino acids have been recently discovered that could result in other applications. For example, oral stimulation by glutamate triggers the cephalic phase response to prepare for food digestion. Further, the stomach and intestines have specific glutamate-recognizing systems in their epithelial mucosa. Regarding clinical applications, addition of monosodium glutamate to the medicinal diet has been shown to markedly enhance gastric secretion in a vagus-dependent manner. Branched-chain amino a...
Source: Advances in Biochemical Engineering Biotechnology - Category: Biotechnology Authors: Tags: Adv Biochem Eng Biotechnol Source Type: research
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