IL-25 ameliorates acute cholestatic liver injury via promoting hepatic bile acid secretion

In conclusion, IL-25 exhibited a protective effect against ANIT-induced cholestatic liver injury in mice, which may be related to the regulation on bile acids secretion. These results provide a theoretical basis for the use of IL-25 in the treatment of cholestatic hepatopathy.PMID:35914403 | DOI:10.1016/j.cyto.2022.155979

Source: Cancer Control - August 1, 2022 Category: Cancer & Oncology Authors: Zewei Zhao Siqi Liu Shiya Luo Lin Zhou Junxi Liu Bingxiu Qian Jianglin Shi Yayun Zhou Jin Li Tao Jiang Zhiyue Lv Zhonghan Yang Source Type: research